--- title: Profil — Clinical trials in diabetes description: Profil is the world's leading CRO in diabetes and obesity research. --- [![profil-logo-wortbild-with claim-4c-offset_1000px](https://www.profil.com/hs-fs/hubfs/profil-logo-wortbild-with%20claim-4c-offset_1000px.png?width=250&name=profil-logo-wortbild-with%20claim-4c-offset_1000px.png "profil-logo-wortbild-with claim-4c-offset_1000px")](https://www.profil.com?hsLang=en-us) [![Contact](https://no-cache.hubspot.com/cta/default/481167/1f89c7d1-107f-4c8d-aa7b-f85d0dce14da.png)](https://cta-redirect.hubspot.com/cta/redirect/481167/1f89c7d1-107f-4c8d-aa7b-f85d0dce14da) [Patient information](https://www.profil.de) ![_MG_0751-112.jpg](https://www.profil.com/hs-fs/hubfs/BLUE_MOON/pikto-profil.png?width=76&height=70&name=pikto-profil.png) ### About Profil Discover the capabilities and expertise of Profil [Read more](https://www.profil.com/organization/about-profil?hsLang=en-us) ![Medical Technology](https://www.profil.com/hs-fs/hubfs/BLUE_MOON/piktos/Icon_MedicalTechnology.png?width=62&height=70&name=Icon_MedicalTechnology.png) ### Medical Technology Profil has a dedicated department for clinical trials of diabetes-related medical devices. [Read more](https://www.profil.com/expertise/medical-technology-research?hsLang=en-us) ![Diabetes Treatment](https://www.profil.com/hs-fs/hubfs/BLUE_MOON/piktos/Icon_DiabetesTreatment.png?width=62&height=70&name=Icon_DiabetesTreatment.png) ### Diabetes Treatment Profil is the partner of choice for clinical studies of diabetes treatments. [Read more](https://www.profil.com/expertise/diabetes-treatment?hsLang=en-us) ![Newsletter registration](https://www.profil.com/hs-fs/hubfs/BLUE_MOON/piktos/Icon_Publications.png?width=74&height=82&name=Icon_Publications.png) ### News at Profil Download our recent conference posters for free. [![Download now](https://no-cache.hubspot.com/cta/default/481167/569591db-6389-4d88-8623-bd6eda10d280.png)](https://cta-redirect.hubspot.com/cta/redirect/481167/569591db-6389-4d88-8623-bd6eda10d280) ## Profil is the world's leading full-service CRO for diabetes and obesity research. As a full-service CRO for early clinical trials in diabetes and obesity, Profil has brought together regulatory and scientific experts so that we can offer you unrivalled service. We focus that expertise on developing sophisticated experimental methods, optimizing study designs, and delivering critical answers for further compound development. Profil began life as a spin-off of an academic study group at the Department of Metabolic Diseases and Nutrition at the University of Düsseldorf. Our founders wished to create a dedicated CRO that would address the challenges of diabetes and obesity research and treatment. The company’s achievements are testament to that vision. Over the years, we have implemented numerous sophisticated methods for [pharmacodynamic characterization](https://www.profil.com/services/pharmacodynamics?hsLang=en-us) of the effects of compounds in early phase trials, and we have been involved in the development of all the currently available major anti-diabetic compounds. Our key competence is the performance of glucose clamp studies, often combined with isotope dilution techniques and muscle or fat biopsies. [Read more](https://www.profil.com/organization/about-profil?hsLang=en-us)   ![blank.jpg](https://www.profil.com/hs-fs/hubfs/BLUE_MOON/piktos/Icon_References.png?width=49&height=49&name=Icon_References.png) #### References We have published with the following sponsors: ![Referenzen](https://www.profil.com/hubfs/BLUE_MOON/content-bilder/Referenzen.gif "Referenzen") [View more](https://www.profil.com/knowledge-center/references?hsLang=en-us) ![blank.jpg](https://www.profil.com/hs-fs/hubfs/BLUE_MOON/piktos/Icon_Certificates.png?width=44&height=49&name=Icon_Certificates.png) #### Certificates | ![13485_Zertifikatssiegel_black_A3](https://www.profil.com/hubfs/BLUE_MOON/piktos/ISO_134852016_certificate_blue.png) ISO 13485:2016 ![27001_Zertifikatssiegel](https://www.profil.com/hubfs/BLUE_MOON/piktos/ISO_27001_certificate_.png) ISO 27001 | ![9001:2015_Zertifikatssiegel](https://www.profil.com/hubfs/BLUE_MOON/piktos/ISO_9001-2015_certificate.png) ISO 9001:2015 ![9001:2015_Zertifikatssiegel](https://www.profil.com/hubfs/BLUE_MOON/piktos/BVMA_Logo_Certificate_size.png) BVMA Member | | --- | --- | ![blank.jpg](https://www.profil.com/hs-fs/hubfs/BLUE_MOON/piktos/Icon_Publications.png?width=44&height=49&name=Icon_Publications.png) #### Publications Marquard J. et al., 2015. Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment. Nature Medicine 21, 363–372 (2015). [View all](https://www.profil.com/knowledge-center/publications?hsLang=en-us) Profil is the leading clinical research organisation for studies related to diabetes and obesity. We conduct pharmacodynamics, pharmacokinetics, biosimilar, safety and tolerability studies, as well as bridging studies and more. We have been involved in the development of an artificial pancreas as part of the AP@home project and have been invovled in the development of all classes of antidiabetic drugs. If you are developing treatments for diabetes mellitus type 1 or diabetes mellitus type 2, then Profil is the right partner for you. ###### Profil Institut für Stoffwechselforschung GmbH Hellersbergstraße 9 · 41460 - Neuss, Germany Telefon +49-2131-4018-345 · marketing@profil.com [Imprint](https://www.profil.com/imprint?hsLang=en-us) | [Privacy Policy](https://www.profil.com/privacy?hsLang=en-us)