Assessing energy expenditure
Profil offers a portfolio of methods for evaluating each component of energy expenditure:
- Resting energy expenditure with indirect calorimetry
- Diet-induced thermogenesis with indirect calorimetry
- Activity-induced energy expenditure with spiroergometry
- Total energy expenditure with the doubly labeled water method
Each method is considered the most accurate available means of measuring the respective aspect of energy expenditure.
Methods for accurately assessing individual energy expenditure are a crucial part of the design of intelligent and comprehensive clinical trials focusing on pharmaceuticals or nutraceuticals for weight management. Total energy expenditure can be divided into three components: resting energy expenditure, diet-induced thermogenesis and activity-induced energy expenditure. Assessing each component enables specific questions to be answered, whereas assessing total energy expenditure permits conclusions about general energy balance and the long-term outcome of a given weight-loss intervention.