--- title: Laser Doppler assessment at Profil description: Laser Doppler assessment is a non-invasive optical measurement offered by Profil for quantifying microvascular blood flow. --- [![profil-logo-wortbild-with claim-4c-offset_1000px](https://www.profil.com/hs-fs/hubfs/profil-logo-wortbild-with%20claim-4c-offset_1000px.png?width=250&name=profil-logo-wortbild-with%20claim-4c-offset_1000px.png "profil-logo-wortbild-with claim-4c-offset_1000px")](https://www.profil.com?hsLang=en-us) [![Contact](https://no-cache.hubspot.com/cta/default/481167/1f89c7d1-107f-4c8d-aa7b-f85d0dce14da.png)](https://cta-redirect.hubspot.com/cta/redirect/481167/1f89c7d1-107f-4c8d-aa7b-f85d0dce14da) [Patient information](https://www.profil.de) # [![Header_Pic1.png](https://www.profil.com/hs-fs/hubfs/BLUE_MOON/Header/Header_1077x260px_Clamp_Art_3.jpg?width=1077&height=260&name=Header_1077x260px_Clamp_Art_3.jpg) Laser Doppler Laser Doppler assessment at Profil](https://www.profil.com/services/laser-doppler#) ## The laser Doppler technique at Profil At Profil, blood flow (BF) is assessed using laser Doppler flowmetry with the probe on the dorsal thenar site of the right hand. Measurements are performed with a continuous-wave laser light. The movement of erythrocytes causes a Doppler shift effect, which is analyzed after reflection for BF. The parameters for measurement are the pre-ischemia BF (piBF) and maximal post-ischemia BF during reactive hyperemia (rBF) after 4.5 min of suprasystolic ischemia of the forearm. The reactive hyperemia reflects the endothelium-dependent vasoreactivity of the microcirculation. Laser Doppler assessment is also used in the context of iontophoresis, local skin heating and sympathetic tests (cold pressure test/deep breath test). The measured parameters are calculated automatically using commercially available software. ![pikto2.png](https://www.profil.com/hs-fs/hubfs/BLUE_MOON/piktos/Icon_NewWebinar.png?width=62&height=70&name=Icon_NewWebinar.png) ### Free  Consultation Are you planning a study? Make sure to request your free project consultation now. [![Request now](https://no-cache.hubspot.com/cta/default/481167/3e4e3d1f-5461-4cd2-84e5-24cfae3c671e.png)](https://cta-redirect.hubspot.com/cta/redirect/481167/3e4e3d1f-5461-4cd2-84e5-24cfae3c671e) ![hans](https://www.profil.com/hs-fs/hubfs/hans.png?width=154&height=176&name=hans.png) ### Our expert **Dr. Hans de Vries** Lead Scientist [![Contact](https://no-cache.hubspot.com/cta/default/481167/3f6ddaea-35ee-4616-bdaf-2db6f28da082.png)](https://cta-redirect.hubspot.com/cta/redirect/481167/3f6ddaea-35ee-4616-bdaf-2db6f28da082) ![blank.jpg](https://www.profil.com/hs-fs/hubfs/BLUE_MOON/piktos/Icon_References.png?width=49&height=49&name=Icon_References.png) #### References We have published with the following sponsors: ![Referenzen](https://www.profil.com/hubfs/BLUE_MOON/content-bilder/Referenzen.gif "Referenzen") [View more](https://www.profil.com/knowledge-center/references?hsLang=en-us) ![blank.jpg](https://www.profil.com/hs-fs/hubfs/BLUE_MOON/piktos/Icon_Certificates.png?width=44&height=49&name=Icon_Certificates.png) #### Certificates | ![13485_Zertifikatssiegel_black_A3](https://www.profil.com/hubfs/BLUE_MOON/piktos/ISO_134852016_certificate_blue.png) ISO 13485:2016 ![27001_Zertifikatssiegel](https://www.profil.com/hubfs/BLUE_MOON/piktos/ISO_27001_certificate_.png) ISO 27001 | ![9001:2015_Zertifikatssiegel](https://www.profil.com/hubfs/BLUE_MOON/piktos/ISO_9001-2015_certificate.png) ISO 9001:2015 ![9001:2015_Zertifikatssiegel](https://www.profil.com/hubfs/BLUE_MOON/piktos/BVMA_Logo_Certificate_size.png) BVMA Member | | --- | --- | ![blank.jpg](https://www.profil.com/hs-fs/hubfs/BLUE_MOON/piktos/Icon_Publications.png?width=44&height=49&name=Icon_Publications.png) #### Publications Jax, T. et al. 2017. A randomised, active- and placebo-controlled, three-period crossover trial to investigate short-term effects of the dipeptidyl peptidase-4 inhibitor linagliptin on macro- and microvascular endothelial function in type 2 diabetes. Cardiovasc Diabetol. 2017 Jan 21;16(1):13. [View all](https://www.profil.com/knowledge-center/publications?hsLang=en-us) Profil offers full support for laser Doppler assessments of microvascular blood flow and for application of the laser Doppler technique in iontophoresis, local skin heating and sympathetic tests (cold pressure test/deep breath test). All of the measurements and calculations are performed by our experts. ###### Profil Institut für Stoffwechselforschung GmbH Hellersbergstraße 9 · 41460 - Neuss, Germany Telefon +49-2131-4018-345 · marketing@profil.com [Imprint](https://www.profil.com/imprint?hsLang=en-us) | [Privacy Policy](https://www.profil.com/privacy?hsLang=en-us)